Well in anime canon they went on some missions together during the time frame Obito would have been recovering in Konoha, so that's probably a solid...maybe...as far as that goes.

She's spent the last five years out of the country but that's like...twelve..years that she'd have still been around after the Kannabi Bridge Incident where they definitely didn't know each other yet? It might be easiest just to assume that they knew each other but only as working associates and go from there, though.